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The possible role of brinzolamide on corneal endothelial function has not been investigated in patients with compromised corneas particularly in patients with low endothelial cell count Specifically, patients is there a generic for azopt eye drops contact lenses have not been studied and careful monitoring of these patients when using brinzolamide is recommended, since carbonic anhydrase inhibitors may affect corneal hydration and wearing contact lenses might increase the risk for the cornea.The result is a reduction in intraocular pressure IOP Following topical ocular administration, brinzolamide is absorbed into the systemic circulation.

Due to its affinity for CA-II, brinzolamide distributes extensively into the RBCs and exhibits a long half-life in whole blood approximately 111 days In humans, the metabolite N-desethyl brinzolamide is formed, which also binds to CA and accumulates in RBCs.

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Azopt works by decreasing the amount of fluid in the eye.Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant.

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If more than one topical ophthalmic purchase azopt is being used, the drugs should be administered at least ten minutes apart.A drug company seeking approval to purchase azopt a purchase azopt equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application ANDA By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart.

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