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Omeprazole
Clinical data
Pronunciation/ oʊ ˈ m ɛ p r ə z oʊ l /
Trade namesLosec, Prilosec, Zegerid, others [1]
AHFS/Drugs.comMonograph
License dataUS   FDA: Omeprazole
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationby mouth, IV
Drug classProton-pump inhibitor
ATC codeA02BC01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability35–76% [2] [3]
Protein binding95%
MetabolismHepatic (CYP2C19, CYP3A4)
Elimination half-life1–1.2 hours
Excretion80% (urine) 20% (feces)

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