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Oncomitant use of fluoxetine and clozapine can increase plasma concentrations of clozapine and enhance clozapine's pharmacologic effects secondary to suspected inhibition of clozapine metabolism by fluoxetine. Increased plasma clozapine concentrations also have been reported in patients receiving other SSRIs e.f you have actavis lamotrigine about the drugs you are taking, check with your doctor, nurse or pharmacist.

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