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Atazanavir, indinavir, ritonavir, saquinavir monoamine oxidase inhibitors MAOIs; e.Some experts recommend delaying breast feeding/milk expression for 3 to 4 hours for patients receiving immediate-release formulations. Adults: Healthy: 2 to 5 hours; Cirrhosis: 7 hours; Elderly: 7 hours extended release tablet Concentration dependent: 92% to 98% Note: Protein-binding may be significantly decreased in patients with renal or hepatic impairment Mean Cmax is 36% higher and plasma concentration is 70% greater in elderly patients.

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WebMD does not endorse any specific product, service, or treatment. Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Patients were instructed to apply the ointment circumferentially 1 cm inside the anus, near the internal anal sphincter, every 8 h for 8 wk.

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The mechanism of this effect is not established.Concomitant oral administration of 1, -dihydropyridine-derivative calcium-channel blocking agents e. nifedipine with grapefruit juice usually should be avoided since potentially clinically important increases in hemodynamic effects may result.

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