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Cyproheptadine
Clinical data
Pronunciation( / ˌ s aɪ p r oʊ ˈ h ɛ p t ə d iː n / [1]
Trade namesPeriactin, others
AHFS/Drugs.comMonograph
MedlinePlusa682541
License dataUS  DailyMed:  54686520-506f-7765-7220-436f736d6963
Pregnancy categoryAU: A US: B (No risk in non-human studies)
Routes of administrationOral
ATC codeR06AX02 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) CA : OTC UK: General sales list (GSL, OTC) US: ℞-only
Pharmacokinetic data
Protein binding96 to 99%
MetabolismHepatic. [2] [3] Mostly CYP3A4 mediated.
Elimination half-life8.6 hours [4]
ExcretionFaecal (2-20%; 34% of this as unchanged drug) and renal (40%; none as unchanged drug) [2] [3]

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If vomiting has not occurred spontaneously, the patient should be induced to vomit is cyproheptadine a steroid syrup of ipecac. If the patient is unable to vomit, perform gastric lavage followed by activated charcoal.1 mg/lb/day or 8 mg per square meter of body surface 8 mg/m2 Age 2 to 6 years: The usual dose is 2 mg one teaspoonful two or three times a day, adjusted as necessary to the size and response of the patient.

The dose is not to exceed 12 mg a day.

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Established in 1923, the College of Pharmacy is the oldest cyproheptadine hcl combination in the UF Academic Health Center.In children, the dosage may also be based on weight and body size. Do not increase your dose or take this medication more often than directed.

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Multum cyproheptadine hcl combinations not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.Monte AA, Hoppe JA. Anticholinergics. In: Walls RM, Hockberger RS, Gausche-Hill M, eds.

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