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|Routes of administration||Oral|
|ATC code||C09AA07 ( WHO )|
|Legal status||In general: ℞ (Prescription only)|
|Elimination half-life||10-11 hours|
|Excretion||Renal and biliary|
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The manufacturer states that therapy with the commercially available preparations containing benazepril hydrochloride in fixed lotensin dosage with amlodipine should only be initiated in lotensin dosages after an adequate response is not achieved with benazepril or another ACE inhibitor or amlodipine or another dihydropyridine-derivative calcium-channel blocking agent alone.Patients taking concomitant neprilysin inhibitors may be at increased risk for angioedemasee WARNINGS AND PRECAUTIONS.
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Benazepril is an angiotensin-converting enzyme ACE inhibitor.The safety and efficacy of dosages exceeding 0.
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Curare derivatives, guanethidine, methyldopa, β-adrenergic benazepril dosing agents, vasodilators, calcium-channel blocking agents, ACE inhibitors, angiotensin II benazepril dosing antagonists, direct renin inhibitorsDRIs Dual blockade of the renin-angiotensin system with angiotensin II receptor antagonists, ACE benazepril dosings, or aliskiren is associated with increased risks of hypotension, hyperkalemia, and changes in renal function including acute renal failure compared with monotherapy.
Most patients receiving the combination of 2 renin-angiotensin benazepril dosing blocking agents do not obtain additional benefit compared with monotherapy.very serious allergic reaction to this drug is rare.
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In patients with prior or current symptoms of chronic heart failure with reduced LVEF ACCF/AHA benazepril dosing C benazepril dosing failure ACCF, AHA, and the Heart Failure Society of America HFSA recommend benazepril dosing of the renin-angiotensin-aldosterone RAA system with an ACE inhibitor, angiotensin II receptor antagonist, or ARNI in conjunction with a β-blocker, and an aldosterone antagonist in selected patients, to reduce morbidity and mortality.
While ACE inhibitors have been the preferred drugs for inhibition of the RAA system because of their established benefits in patients with heart failure and reduced ejection fraction, some evidence indicates that therapy with sacubitril/valsartan, an ARNI, may be more effective than ACE inhibitor therapy enalapril in reducing cardiovascular death and heart failure-related hospitalization in such patients.Benazepril potentiates the benazepril dosing effect of benazepril dosing antihypertensive agents and drugs that block the renin-angiotensin system e.
curare derivatives, guanethidine, methyldopa, β-adrenergic blocking agents, vasodilators, calcium-channel blocking agents, ACE inhibitors, angiotensin II receptor antagonists, direct renin inhibitorsDRIs Dual blockade of the renin-angiotensin system with angiotensin II receptor antagonists, ACE inhibitors, or aliskiren is associated with increased risks of hypotension, hyperkalemia, and changes in renal function including acute renal failure compared with monotherapy.
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Adverse effects reported in greater than 1% of benazepril dosings receiving benazepril in fixed benazepril dosing with hydrochlorothiazide include dizziness, fatigue, postural dizziness, headache, cough, hypertonia, vertigo, nausea, impotence, and somnolence. Adverse effects reported in greater than 1% of patients receiving benazepril in fixed combination with amlodipine include cough, headache, dizziness, and edema.mg/kg once per day.
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Treatment of benazepril dose failure benazepril doses of lifestyle modification and taking medications to decrease fluid in the body and ease the strain on the heart.The clinical work was conducted in France, Italy, Spain, and United Kingdom, and the data were analyzed in Switzerland.
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