The following undesirable effects were reported at an incidence greater than placebo in clinical trials in patients with OA, RA, chronic low back pain or ankylosing spondylitis treated with etoricoxib 30 mg, 60 mg or 90 mg up to the recommended dose for up to 12 weeks; in the MEDAL Programme studies for up to 3 years; in short term acute pain studies for up to 7 days; or in post-marketing experience (see Table 1) anaemia (primarily associated with gastrointestinal bleeding) leukopenia, thrombocytopenia atrial fibrillation, tachycardia, congestive heart failure, non-specific ECG changes, angina pectoris, myocardial infarction flushing, cerebrovascular accident, transient ischaemic attack, hypertensive crisis, vasculitis Constipation, flatulence, gastritis, heartburn/acid reflux, diarrhea, dyspepsia/epigastric discomfort, nausea, vomiting, oesophagitis, oral ulcer abdominal distention, owel movement pattern change, dry mouth, gastroduodenal ulcer, peptic ulcers including gastrointestinal perforation and bleeding, irritable bowel syndrome, pancreatitis proteinuria, serum creatinine increased, renal failure/renal insufficiency (see section 4. Etoricoxib (arcoxia) pkg. 120 mg 120 the amount of packaging.
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hickories maximum of 42. pings, median 21. tents In this topic, only serious gastrointestinal symptoms and discontinuations due to any unusual thoughts were recorded.
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For acute pain conditions, etoricoxib should be used only for the etoricoxib cost uk symptomatic period. The recommended dose is 120 mg once daily.2 mm The MEDAL Programme was a prospectively designed Cardiovascular CV Safety Outcomes Programme of pooled data from three randomized, double-blind active comparator controlled trials, the MEDAL study, EDGE II and EDGE.
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Etoricoxib should be discontinued at the first appearance of skin rash, mucosal lesions, or any other sign of hypersensitivity.
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Regardless of indication, in patients with mild etoricoxib cost uk dysfunction Child-Pugh score 5-6 a dose of 60 mg once daily should not be exceeded. In patients with moderate etoricoxib cost uk dysfunction Child-Pugh score 7-9 regardless of indication, the dose of 30 mg once daily should not be exceeded.Any patients with symptoms and/or signs suggesting liver dysfunction, or in whom an abnormal liver function test has occurred, should be monitored.
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